Other findings include sinus node dysfunction, sinoatrial blocks, PR prolongation, QT prolongation/dispersion, and ventricular tachyarrhythmias. T wave inversion was the most frequently reported ECG finding. A total of 406 articles were found on literature search, of which 56 met the screening criteria. A systematic literature search was conducted on 2 electronic databases-PubMed and Medline-for the time period between January 1970 and March 2016 using the key word “lithium,” along with “electrocardiography” or “ECG.” All articles and their references were then screened by title for relevance by 2 authors and a librarian.
Reports of cardiac side effects resulting in both benign electrocardiographic (ECG) changes and near fatal arrhythmias have been reported in the literature.
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Lithium has been used for the treatment of bipolar disorder for more than 6 decades.
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